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    • br The Journal of Thoracic and Cardiovascular

    2020-08-30


    The Journal of Thoracic and Cardiovascular Surgery c Volume 158, Number 2 577
    Thoracic: Lung Cancer Moore et al
    THOR
    Conflict of Interest Statement
    Authors have nothing to disclose with regard to commercial support.
    References
    1. US Cancer Statistics. Leading cancer cases and deaths, male and female, 2015. Available at: https://nccd.cdc.gov/uscs/cancersbyraceandethnicity.aspx. Accessed April 5, 2018.
    2. National Cancer Institute Surveillance, Epidemiology, and End Results Program. Table 15.14. Non-small cell cancer of the lung and bronchus (invasive): 5-year relative and Cortistatin14TFA survival by race, sex, diagnosis year, age and stage at diag-nosis. Available at: https://seer.cancer.gov/csr/1975_2014/browse_csr.php? sectionSEL¼15&pageSEL¼sect_15_table.14.html. Accessed April 5, 2018.
    3. STS Public Reporting Online. General surgery public reporting. Available at: https://publicreporting.sts.org/gtsd. Accessed April 4, 2018.
    4. LaPar DJ, Bhamidipati CM, Lau CL, Jones DR, Kozower BD. The Society of Thoracic Surgeons general thoracic surgery database: establishing generalizability to national lung cancer resection outcomes. Ann Thorac Surg. 2012;94:216-21.
    5. McMillan RR, Berger A, Sima CS, Lou F, Dycoco J, Rusch V, et al. Thirty-day mortality underestimates the risk of early death after major resections for thoracic malignancies. Ann Thorac Surg. 2014;98:1769-74.
    7. In H, Palis BE, Merkow RP, Posner MC, Ferguson MK, Winchester DP, et al. Doubling of 30-day mortality by 90 days after esophagectomy: a crit- 
    ical measure of outcomes for quality improvement. Ann Surg. 2016;263:
    8. American College of Surgeons National Cancer Database. Available at: https:// www.facs.org/quality-programs/cancer/ncdb. Accessed April 3, 2018.
    9. Edge S, Byrd DR, Compton CC, Fritz AG, Greene F, Trotti A, eds. AJCC Cancer Staging Handbook. New York: Springer-Verlag; 2010.
    10. International Classification of Diseases for Oncology. ICD-O-3 Online. Avail-able at: http://codes.iarc.fr/. Accessed April 4, 2018.
    11. Pedersen AB, Mikkelsen EM, Cronin-Fenton D, Kristensen NR, Pham TM, Pedersen L, et al. Missing data and multiple imputation in clinical epidemiolog-ical research. Clin Epidemiol. 2017;9:157-66.
    14. Hu Y, McMurry TL, Wells KM, Isbell JM, Stunkeborg GJ, Kozower BD. Post-operative mortality is an inadequate quality indicator for lung cancer resection. Ann Thorac Surg. 2014;97:973-9.
    Key Words: 30-day mortality, 90-day mortality, quality metrics, hospital ranking, lung cancer surgery, National Cancer Database (NCDB)
    578 The Journal of Thoracic and Cardiovascular Surgery c August 2019
    Moore et al Thoracic: Lung Cancer
    TABLE E1. Three variables with missingness were imputed. The
    percent missing in each of endoderm variables are shown
    Number missing (%)
    Facility type
    THOR
    The Journal of Thoracic and Cardiovascular Surgery c Volume 158, Number 2 578.e1
    Thoracic: Lung Cancer Moore et al
    THOR
    TABLE E2. Comparison of 30-day mortality generalized logistic model using completed imputed data set compared with the original data set where patients with missingness in facility type, median income, and urban versus rural location variables are dropped
    30-d Mortality imputed
    30-d Mortality without imputation
    Variable
    OR LL UL
    OR
    LL UL
    Reference
    Reference
    Sex
    Female
    Reference
    Reference
    Male
    Race
    White
    Reference
    Reference
    Black
    Comorbidities
    Insurance status
    Not insured
    Reference
    Reference
    Private insurance
    Medicaid
    Medicare
    Other government insurance
    Unknown
    Income
    Median income quartiles
    Year of diagnosis
    Primary site*
    C340—Main bronchus
    Reference
    Reference
    C348—Overlapping
    C349—Not otherwise specified
    Analytic stage
    Reference
    Reference
    I
    III
    IV
    Occult
    Unknown
    Histology
    1—Adenocarcinoma
    Reference
    Reference
    3—Carcinoid
    Grade
    (Continued)
    578.e2 The Journal of Thoracic and Cardiovascular Surgery c August 2019
    Moore et al Thoracic: Lung Cancer
    TABLE E2. Continued
    30-d Mortality imputed
    30-d Mortality without imputation Variable OR LL UL
    OR LL UL
    Neoadjuvant therapy
    No Reference
    Reference
    Facility type
    Community Reference
    Reference